Sasirome RacochoteManat PohmakotrChutima KuhakarnPawaret LeowanawatVichai ReutrakulDarunee SoorukramMahidol University2020-01-272020-01-272019-03-31European Journal of Organic Chemistry. Vol.2019, No.12 (2019), 2212-2223109906901434193X2-s2.0-85060334645https://repository.li.mahidol.ac.th/handle/20.500.14594/50573© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Asymmetric synthesis of trifluoromethylated derivative of ent-fragransin C 1 was reported. The installation of contiguous stereochemistries across the tetrahydrofuran scaffold was achieved through stereocontrolled conjugate addition, aldol reaction, and a protection-free intramolecular C-O bond formation (furan ring formation) via chemoselective generation of the benzylic carbocation.Mahidol UniversityChemistryArticleSCOPUS10.1002/ejoc.201801676