Supanan AmpawaChanin KethongJiraya KiriratnikomKhamphee PhomphraiPreeyanuch SangtrirutnugulVidyasirimedhi Institute of Science and TechnologyMahidol University2019-08-232019-08-232018-04-30ChemistrySelect. Vol.3, No.16 (2018), 4156-4162236565492-s2.0-85046096250https://repository.li.mahidol.ac.th/handle/20.500.14594/45497© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim PdII-bis(triazolyl)phenylmethanol complexes bearing different groups (i. e., H, OMe, OH, COOH) directly attached to the benzyl rings were explored as precatalysts for copper-free Sonogashira and Suzuki–Miyaura coupling reactions in water. Crystal structures reveal a bidentate N,N binding mode of the bis(triazolyl) ligands affording a distorted square planar PdII complexes. With the exception of the phenol-substituted bis(triazolyl) ligands, the other three Pd complexes exhibited high activities toward Suzuki–Miyaura coupling reactions. Transmission electron microscopy (TEM) study and PPh3 poisoning experiments confirm that bis(triazoly)-stabilized Pd nanoparticles (Pd NPs) were generated in situ during the catalytic reactions and involved as one of the active catalytic species in the Suzuki–Miyaura cross coupling.Mahidol UniversityChemistryArticleSCOPUS10.1002/slct.201800822