Somdej KanokmedhakulKwanjai KanokmedhakulThirada PrajuabsukSanha PanichajakulPiyanan PanyameeSamran PrabpaiPalangpon KongsaereeKhon Kaen UniversityMahidol University2018-06-212018-06-212005-07-01Journal of Natural Products. Vol.68, No.7 (2005), 1047-1050016338642-s2.0-23844514717https://repository.li.mahidol.ac.th/handle/20.500.14594/16322Three new azadirachtin derivatives, named azadirachtins O-Q (1-3), along with the known azadirachtin B (4), azadirachtin L (5), azadirachtin M (6) 11α-azadirachtin H (7), 11β-azadirachtin H (8), and azadirachtol (9) were isolated from seed kernels of Azadirachta excelsa. Their structures were established by spectroscopic techniques, and the structure of 3 was confirmed by X-ray analysis. Compounds 1-7 and 9 exhibited toxicity to the diamondback moth (Plutella xylostella) with an LD50 of 0.75-1.92 μg/g body weight, in 92 h. © 2005 American Chemical Society and American Society of Pharmacognosy.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryMedicinePharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1021/np050064t