Lack of association between toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus

Catrin E. MooreShelley SegalAnthony R. BerendtAdrian V.S. HillNicholas P.J. DayJohn Radcliffe HospitalNuffield Orthopaedic Centre NHS TrustMahidol UniversityUniversity of Oxford2018-07-242018-07-242004-11-01Clinical and Diagnostic Laboratory Immunology. Vol.11, No.6 (2004), 1194-11971071412X2-s2.0-9144264994https://repository.li.mahidol.ac.th/handle/20.500.14594/21140To investigate a putative link between genetically determined variations in Toll-like receptor 2 (TLR2) and the occurrence of severe Staphylococcus aureus infection, the functional Arg753Gln single-nucleotide polymorphism and the GT repeat microsatellite in the TLR2 gene were examined in a large case-control study. No associations with disease or mortality attributable to these features were found.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicineLack of association between toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureusArticleSCOPUS10.1128/CDLI.11.6.1194-1197.2004