Petra ZürbigHassan DihaziJochen MetzgerVisith ThongboonkerdAntonia VlahouMosaiques Diagnostics GmbHUniversitat GottingenMahidol UniversityAcademy of Athens2018-05-032018-05-032011-06-01Proteomics - Clinical Applications. Vol.5, No.5-6 (2011), 256-26818628354186283462-s2.0-79957589086https://repository.li.mahidol.ac.th/handle/20.500.14594/11544To date, multiple biomarker discovery studies in urine have been conducted. Nevertheless, the rate of progression of these biomarkers to qualification and even more clinical application is extremely low. The scope of this article is to provide an overview of main clinically relevant proteomic findings from urine focusing on kidney diseases, bladder and prostate cancers. In addition, approaches for promoting the use of urine in clinical proteomics including potential means to facilitate the validation of existing promising findings (biomarker candidates identified from previous studies) and to increase the chances for success for the identification of new biomarkers are discussed. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyReviewSCOPUS10.1002/prca.201000133