Dusitkasem S.Sirimusika T.Komonhirun R.Mahidol University2026-03-022026-03-022026-01-01Journal of the Medical Association of Thailand Vol.109 No.2 (2026) , 162-17401252208https://repository.li.mahidol.ac.th/handle/123456789/115492Microsurgical free flap reconstruction remains the primary standard of care for managing complex defects, following advanced head and neck cancer resections. Although success rates have improved substantially, these complex procedures represent a major challenge to achieve the optimum patient and flap outcomes. Recent advances in preoperative evaluation and anesthetic management focus on patient optimization and perioperative care to maximize free flap survival and reduce complications.MedicineArticleSCOPUS10.35755/jmedassocthai.2026.2.032222-s2.0-10503100778824081981