Huang W.Yang Z.Zhang Y.Vogt T.Park J.Yu W.Xu R.Hales S.Hundessa S.Otto C.Yu P.Liu Y.Ju K.Lavigne E.Ye T.Wen B.Wu Y.Zhang Y.Kliengchuay W.Tantrakarnapa K.Guo Y.L.Kim H.Phung D.Ritchie E.A.Li S.Guo Y.Mahidol University2025-08-172025-08-172025-08-01Science Advances Vol.11 No.31 (2025) , eadr0800https://repository.li.mahidol.ac.th/handle/20.500.14594/111706The indirect health risks of tropical cyclones (TCs), the costliest climate extremes, remain unclear, with cardiovascular diseases (CVDs) being a major contributor. We applied two-stage time-series analysis to 6.54 million CVD hospitalizations across six countries/territories (Canada, New Zealand, South Korea, Taiwan, Thailand, and Vietnam) between 2000 and 2019 to quantify the long-term risks and burden of CVD hospitalizations following TCs. Hospitalization risks for cause-specific CVDs consistently increased following TC exposure, generally peaking around 2 months postexposure and dissipating by 6 months. Overall, each additional TC day was associated with a 13% (95% confidence interval, 7 to 19%) increase in CVD hospitalizations in 6 months following TCs. Particularly high TC-attributable burden was found for ischemic heart diseases and stroke, especially among males, individuals aged 20 to 59 years, and those with higher levels of socioeconomic deprivation. The TC-attributable proportions of CVD hospitalizations showed decreasing trends in less deprived populations and increasing trends in more deprived populations from 2000 to 2019.MultidisciplinaryArticleSCOPUS10.1126/sciadv.adr08002-s2.0-1050129102922375254840749061