Sungha ParkKazuomi KarioYook Chin ChiaYuda TuranaChen Huan ChenPeera BuranakitjaroenJennifer NailesSatoshi HoshideSaulat SiddiqueJorge SisonArieska Ann SoenartaGuru Prasad SogunuruJam Chin TayBoon Wee TeoYu Qing ZhangJinho ShinHuynh Van MinhNaoko TomitaniTomoyuki KabutoyaApichard SukonthasarnNarsingh VermaTzung Dau WangJi Guang WangUniversity Medicine and Pharmacy, Hue UniversityDe La Salle Health Sciences InstituteSunway UniversityHanyang University Medical CenterJichi Medical UniversityShanghai Jiao Tong University School of MedicineMadras Institute of Orthopaedics and Traumatology HospitalsKathmandu UniversityUniversity of the East Ramon Magsaysay Memorial Medical CenterFatima Memorial HospitalUniversitas Katolik Indonesia Atma JayaUniversitas IndonesiaUniversity of MalayaFuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical CollegeYong Loo Lin School of MedicineNational Taiwan University College of MedicineKing George's Medical UniversityYonsei University College of MedicineFaculty of Medicine, Siriraj Hospital, Mahidol UniversityNational Yang-Ming University, School of MedicineTan Tock Seng HospitalChiang Mai University2020-05-052020-05-052020-03-01Journal of Clinical Hypertension. Vol.22, No.3 (2020), 438-44417517176152461752-s2.0-85076747045https://repository.li.mahidol.ac.th/handle/20.500.14594/54623© 2019 Wiley Periodicals, Inc. Epidemiologic studies have consistently demonstrated an increased risk of cardiovascular disease during colder temperatures. Hemodynamic changes associated with cold temperature and an increase in thrombogenicity may both account for the increase in cardiovascular risk and mortality. Studies using both in-office and out-of-office BP measurements have consistently shown an elevation in BP during the colder seasons. The large difference in BP between cold and warm months may increase the incidence of hypertension and reduce the hypertension control rate, potentially resulting in increased cardiovascular risk, especially among those at risk of cardiovascular disease. The current trends in global warming and climate change may have a profound impact on the epidemiology of hypertension and cardiovascular disease, as changes in the climate may significantly affect both BP variability and cardiovascular disease, especially in those with high cardiovascular risk and the elderly. Furthermore, climate change could have a significant influence on hypertension in Asia, considering the unique characteristics of hypertensive patients in Asia. As an increase in ambient temperature decreases the mean daytime average and morning surge in BP, but increases the nocturnal BP, it is difficult to predict how environmental changes will affect the epidemiology and prognosis of hypertension in the Asian-Pacific region. However, these seasonal variations in BP could be minimized by adjusting the housing conditions and using anticipation medicine. In this review, we discuss the impact of seasonal variation in the ambient temperature on hypertension and cardiovascular disease and discuss how this may impact the epidemiology of hypertension and cardiovascular disease.Mahidol UniversityMedicineReviewSCOPUS10.1111/jch.13762