Koen Van BesienClaire VerschraegenRakesh MehraSergio GiraltAndrzej P. KudelkaCreighton L. EdwardsSurintip PiamsonboomWichai TermrungruanglertRichard ChamplinJohn J. KavanaghUniversity of Texas MD Anderson Cancer CenterMahidol UniversityChulalongkorn University2018-07-042018-07-041997-01-01Gynecologic Oncology. Vol.65, No.2 (1997), 366-369009082582-s2.0-0031148788https://repository.li.mahidol.ac.th/handle/20.500.14594/18213Patients with chemotherapy-refractory gestational trophoblastic disease and brain metastasis are considered to have a very poor prognosis. We present the case of a patient who had failed several chemotherapeutic regimens. Despite transient responses to chemotherapy, she had not achieved a complete remission in 3 years, and had developed systemic disease and recurrent brain metastasis. She was treated with four cycles of high-dose ifosfamide, carboplatin, and etoposide with blood progenitor cell support. She tolerated this regimen well and has obtained a complete remission that is ongoing for 12 months.Mahidol UniversityMedicineComplete remission of refractory gestational trophoblastic disease with brain metastases treated with multicycle ifosfamide, carboplatin, and etoposide (ICE) and stem cell rescueArticleSCOPUS10.1006/gyno.1997.4677