Praewpan KatrunSornsiri HlekhlaiJatuporn MeesinManat PohmakotrVichai ReutrakulThaworn JaipetchDarunee SoorukramChutima KuhakarnMahidol University2018-11-232018-11-232015-04-28Organic and Biomolecular Chemistry. Vol.13, No.16 (2015), 4785-4794147705202-s2.0-84927615292https://repository.li.mahidol.ac.th/handle/20.500.14594/35464© The Royal Society of Chemistry 2015. A highly efficient metal-free decarboxylative sulfonylation protocol for the preparation of (E)-vinyl sulfones from of β-aryl-α,β-unsaturated carboxylic acids using sodium sulfinates and (diacetoxyiodo)benzene (PhI(OAc)<inf>2</inf>) was developed. This strategy offers a simple and expedient synthesis of (E)-vinyl sulfones bearing a wide variety of functional groups. A radical-based pathway has been proposed for this decarboxylative sulfonylation reaction.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPhI(OAc)&lt;inf&gt;2&lt;/inf&gt; mediated decarboxylative sulfonylation of β-aryl-α,β-unsaturated carboxylic acids: A synthesis of (E)-vinyl sulfonesArticleSCOPUS10.1039/c5ob00417a