Patompong UngprasertAnawin SanguankeoSikarin UpalaPromporn SuksaranjitMahidol UniversityUniversity of Utah, School of Medicine2018-11-092018-11-092014-10-01QJM. Vol.107, No.10 (2014), 793-79714602393146027252-s2.0-84938751565https://repository.li.mahidol.ac.th/handle/20.500.14594/34183© The Author 2014. Published by Oxford University Press on behalf of the Society of Toxicology. Background: Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, have been shown to increase venous thromboembolism (VTE) risk but the data on psoriasis is unclear. Methods:Weconducted a systematic review andmetaanalysis of observational studies that reported odds ratio, relative risk, hazard ratio or standardized incidence ratio comparing VTE risk in patients with psoriasis vs. non-psoriasis participants. Pooled risk ratio and 95% confidence intervals were calculated using a random effect, generic inverse variance method. Result: Four studies were identified and included in our data analysis. The pooled risk ratio of VTE in patients with psoriasis was 1.46 (95% CI, 1.29- 1.66). The statistical heterogeneity of this meta-analysis was high with an I2 of 86%. Conclusion: Our study demonstrated a statistically significant increased VTE risk among patients with psoriasis.Mahidol UniversityMedicineArticleSCOPUS10.1093/qjmed/hcu073