Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.

Naowarat Tanomsingเนาวรัตน์ ถนอมสิงห์Mayxay, MayfongNewton, Paul N.Nosten, FrancoisDolecek, ChristianeHien, Tran TinhWhite, Nicholas J.Day, Nicholas P. J.Dondorp, Arjen M.Mallika Imwongมัลลิกา อิ่มวงศ์Mahidol University. Faculty of Tropical Medicine. Department of Molecular Tropical Medicine and GeneticsMahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research UnitMahidol University. Faculty of Tropical Medicine. Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Uni.2015-02-242016-10-052015-02-242016-10-0520142015-02-232014-04-03Tanomsing N, Mayxay M, Newton PN, Nosten F, Dolecek C, Hien TT. et al. Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries. PLoS One. 2014 Apr 3;9(4):e93942.1932-6203 (electronic)https://repository.li.mahidol.ac.th/handle/20.500.14594/772The dihydropteroate synthase (dhps) genes of 44 P. malariae strains from four Asian countries were isolated. Only a limited number of polymorphisms were observed. Comparison with homologous mutations in other Plasmodium species showed that these polymorphisms are unlikely to be associated with sulfadoxine resistance.engMahidol UniversityAntimalarialsDNA, ProtozoanPlasmodium malariaeSulfadoxineOpen Access articleGenetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.ArticlePLOS ONE10.1371/journal.pone.0093942.