Tetrahydro-1,4-epoxynaphthalene-1-carboxylic acid: a chiral resolving agent for the resolution and absolute configuration assignment of 7,7'-disubstituted 1,1'-bi-2-naphthols

Kulvadee DolsophonNopporn RuangsupapichatJakapun SoponpongSuttipun SungsuwanSamran PrabpaiPalangpon KongsaereeTienthong ThongpanchangMahidol UniversityThailand National Center for Genetic Engineering and Biotechnology2018-12-112019-03-142018-12-112019-03-142016-01-01Tetrahedron Asymmetry. Vol.27, No.22-23 (2016), 1113-11201362511X095741662-s2.0-84994267567https://repository.li.mahidol.ac.th/handle/20.500.14594/43340© 2016 Elsevier Ltd Tetrahydro-1,4-epoxynaphthalene-1-carboxylic acid (THENA), was applied as a chiral derivatizing agent to resolve 7,7'-disubstituted 1,1'-bi-2-naphthol derivatives. This process is very efficient and could potentially be used as a preliminary tool to assign the absolute configuration of substituted 1,1'-bi-2-naphthols by means of a simple TLC.Mahidol UniversityChemical EngineeringChemistryTetrahydro-1,4-epoxynaphthalene-1-carboxylic acid: a chiral resolving agent for the resolution and absolute configuration assignment of 7,7'-disubstituted 1,1'-bi-2-naphtholsArticleSCOPUS10.1016/j.tetasy.2016.09.003