B. PongpanichS. BoonpucknavigC. WasiP. TanphaichitrV. BoonpucknavigFaculty of Medicine, Ramathibodi Hospital, Mahidol UniversityMahidol University2018-10-122018-10-121983-09-01Clinical Rheumatology. Vol.2, No.3 (1983), 217-22214349949077031982-s2.0-0020812508https://repository.li.mahidol.ac.th/handle/20.500.14594/30504Immunopathologic studies were performed on heart tissue of patients with acute rheumatic fever with carditis and chronic rheumatic heart disease. Coxsackie group B viral antigen was demonstrated in 3 heart specimens of patients clinically compatible with active rheumatic fever. In two of these the pathologic findings were compatible with acute rheumatic carditis. Immunoglobulin was detected in 2 and complement in one of these heart specimens. All of the chronic rheumatic heart specimens and the controls were negative. These findings suggested that Coxsackie group B virus may be etiologically related to the pathogenesis of acute rheumatic fever. © 1983 Springer-Verlag.Mahidol UniversityMedicineArticleSCOPUS10.1007/BF02041393