Paul N. NewtonMichele Van VugtPaktiya Teja-IsavadharmDuangsuda SiriyanondaManeerat RasameesorojPramote TeerapongRonatrai RuangveerayuthThra SlightFrancois NostenYupin SuputtamongkolSornchai LooareesuwanNicholas J. WhiteMahidol University2018-07-242018-07-242002-04-09Antimicrobial Agents and Chemotherapy. Vol.46, No.4 (2002), 1125-1127006648042-s2.0-0036207484https://repository.li.mahidol.ac.th/handle/20.500.14594/20503Plasma antimalarial activity following oral artesunate or dihydroartemisinin (DHA) treatment was measured by a bioassay in 18 patients with uncomplicated faiciparum malaria. The mean antimalarial activity in terms of the bioavailability of DHA relative to that of artesunate did not differ significantly from 1, suggesting that DHA can be formulated to be an acceptable oral alternative to artesunate.Mahidol UniversityMedicinePharmacology, Toxicology and PharmaceuticsComparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malariaArticleSCOPUS10.1128/AAC.46.4.1125-1127.2002