V. ViranuvattiC. DamrongsakT. ChainuvatS. HitanantMahidol University2018-04-302018-04-301980-12-01Annals of the Academy of Medicine Singapore. Vol.9, No.2 (1980), 196-198030446022-s2.0-0019156134https://repository.li.mahidol.ac.th/handle/20.500.14594/11145During the past 20 years, trends have been observed in primary hepatocellular carcinoma in Thailand. There is a definite increase in the association between HCC and cirrhosis of the liver from 16.6% in 1958 to 50.78% in 1968 and 73.93% in the 1978 series. The increase in percentage is associated with an increase in the mean age from 44.61 ± 9.77 in 1958, to 48.84 ± 12.35 (p < 0.01) in 1978. This reflects the important role which hepatitis B plays in the etiology of HCC associated with cirrhosis in Thailand. Also, the aggregation of people in the city of Bangkok may cause an increase in the hepatitis B carrier.Mahidol UniversityMedicineArticleSCOPUS