Matthew M. IppolitoJeffrey M. JacobsonMichael M. LedermanMarkus WinterbergJoel TarningTheresa A. ShapiroCharles FlexnerTemple UniversityMahidol UniversityNuffield Department of Clinical MedicineJohns Hopkins Bloomberg School of Public HealthJohns Hopkins UniversityCase Western Reserve University2019-08-232019-08-232018-10-30Clinical Infectious Diseases. Vol.67, No.10 (2018), 1617-162015376591105848382-s2.0-85055631898https://repository.li.mahidol.ac.th/handle/123456789/46240© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. The effect of antiretroviral therapy (ART) on chloroquine and desethyl-chloroquine plasma concentrations was evaluated in clinical trial participants. Concentrations did not differ among participants receiving protease inhibitor-based ART (n = 9), efavirenz-based ART (n = 15), or other ART (n = 8) and those not receiving ART (n = 31). Efavirenz seemed to inhibit chloroquine desethylation.Mahidol UniversityMedicineEffect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquineArticleSCOPUS10.1093/cid/ciy405