P. KraivaphanC. AmornchatT. TriratanaMahidol University2018-08-242018-08-242007-05-01Southeast Asian Journal of Tropical Medicine and Public Health. Vol.38, No.3 (2007), 594-597012515622-s2.0-34547341306https://repository.li.mahidol.ac.th/handle/123456789/24878The objective of this study was to determine the effects of a triclosan/copolymer dentifrice on plaque formation, gingivitis and gingival bleeding in pregnant subjects. This doubleblind clinical study was carried out in 180 women at 3 months of pregnancy. The subjects were stratified into two balanced groups according to their baseline plaque, gingivitis and bleeding scores. Subjects received a thorough dental prophylaxis and were assigned to brush with either a placebo or triclosan dentifrice for five months. They were instructed to brush their teeth as they normally would, twice a day for one minute per brushing. Follow-up examinations after five months of dentifrice use evaluated supragingival plaque, gingivitis and gingival bleeding. After five months, the triclosan dentifrice significantly reduced plaque formation, gingivitis and gingival bleeding by 40.5%, 22.5% and 35.3%, respectively, compared to the placebo group (p<0.05).Mahidol UniversityMedicineArticleSCOPUS