Merel KimmanPrin VathesatogkitMark WoodwardE. Shyong TaiJulian ThumbooSukit YamwongWipa RatanachaiwongHwee Lin WeePiyamitr SritaraGeorge Institute for Global HealthUniversity of Sydney Faculty of MedicineMahidol UniversityNational University Health SystemSingapore General HospitalMedical and Health OfficeNational University of Singapore2018-10-192018-10-192013-08-01Quality of Life Research. Vol.22, No.6 (2013), 1499-1506096293432-s2.0-84885177589https://repository.li.mahidol.ac.th/handle/20.500.14594/32241Purpose: To assess the construct validity of the Thai EuroQoL (EQ-5D) among an occupational population in Thailand. Methods: Data were derived from a large cohort study among employees of the Electricity Generating Authority of Thailand. In 2008 and 2009, 4,850 participants completed the Thai EQ-5D and Short-Form 36 version 2 (SF-36v2). Thai preferences weights were used to convert EQ-5D health states into EQ-5D index scores. Construct validity of the Thai EQ-5D was examined by specifying and testing hypotheses about the relationships between the EQ-5D, SF-36v2, and participants' demographic and medical characteristics. Results: Construct validity of the Thai EQ-5D was supported by expected relationships with SF-36v2 scale and summary scores. For example, SF-36v2 scores on the mental health scale were much lower for participants who reported having problems on the EQ-5D anxiety/depression dimension compared to those reporting no problems (mean norm-based SF-36v2 scores: 52.9 vs. 41.8, p < 0.001). Additionally, reporting a problem in a given EQ-5D dimension was generally associated with lower SF-36v2 summary scores. The EQ-5D index score distinguished between groups of participants in the expected manner, on the basis of sex, age, education and self-reported health, thus providing evidence of known-groups validity. Conclusion: The study demonstrated good construct validity of the Thai EQ-5D in a large occupational population in Thailand. © 2012 Springer Science+Business Media B.V.Mahidol UniversityMedicineArticleSCOPUS10.1007/s11136-012-0251-2