Joel TarningNiklas LindegårdhAnna AnnerbergThida SingtorojNicholas P.J. DayMichael AshtonNicholas J. WhiteGoteborg University, Sahlgrenska AcademyMahidol University2018-06-212018-06-212005-12-01Antimicrobial Agents and Chemotherapy. Vol.49, No.12 (2005), 5127-5128006648042-s2.0-28844503112https://repository.li.mahidol.ac.th/handle/20.500.14594/16719By using a sensitive new assay, the terminal elimination half-life of the antimalarial piperaquine in a healthy volunteer was estimated to be 33 days, which is longer than estimated previously. This result illustrates the importance of extended sampling duration and sensitive assay methodologies in characterizing the disposition of slowly eliminated antimalarial drugs. Copyright © 2005, American Society for Microbiology. All Rights Reserved.Mahidol UniversityMedicinePharmacology, Toxicology and PharmaceuticsPitfalls in estimating piperaquine eliminationArticleSCOPUS10.1128/AAC.49.12.5127-5128.2005