Chakapong IntaraudomNattawut BoonyuenSumalee SupothinaPunsa TobworSamran PrabpaiPalangpon KongsaereePattama PittayakhajonwutThailand National Center for Genetic Engineering and BiotechnologyFaculty of ScienceMahidol University2018-10-192018-10-192013-01-01Phytochemistry Letters. Vol.6, No.3 (2013), 345-34918767486187439002-s2.0-84877837406https://repository.li.mahidol.ac.th/handle/20.500.14594/31118novel spiro-sesquiterpene, anthracophyllic acid (1), and a new aristolane sesquiterpene, anthracophyllone (2), were isolated from the mushroom Anthracophyllum sp. BCC18695, together with seven known compounds including aurisins A (3), G (4), K (5), nambinones A, C, axinysones A, and B. The relative configuration of 1 and the hitherto unknown absolute stereochemistry of 3 were determined based on X-ray spectroscopic data. Biological activities including antimalarial activity against Plasmodium falciparum K1 strain, antibacterial property against Bacillus cereus, and cytotoxicity against MCF-7, KB, NCI-H187, and Vero cells of the isolated compounds were also evaluated. © 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.Mahidol UniversityAgricultural and Biological SciencesBiochemistry, Genetics and Molecular BiologyNovel spiro-sesquiterpene from the mushroom Anthracophyllum sp. BCC18695ArticleSCOPUS10.1016/j.phytol.2013.04.006