Thirayudh GlinsukonPipat CherdrungsiChote Posri2025-02-032025-02-03199020251990Thesis (M.Sc. (Physiology))--Mahidol University, 1990https://repository.li.mahidol.ac.th/handle/20.500.14594/103228Physiology (Mahidol University 1990)The effect of mini-marathon running on microvascular hemolysis and hematuria was investigated in 33 male students from Faculty of Forestry, Kasetsart University. The age, weight, and height were 20.5 ± 0.3 years, 56.9 ± 0.4 kg and 169.2 ± 0.8 cm. respectively. The microvascular hemolysis were identified by plasma hemoglobin and hemoglobinuria. Hematuria were determined by direct examination with light microscopy (red blood cells/high power filed). The subject screening included medical histroy, physical examination, hematological analysis, blood chemistry determination and urine analysis. Urine and blood collection was obtained before and immediately after mini-marathon running (15 km). Before mini-marathon running, urine concentration of total protein and albumin were 86.63 ± 14.8 mg% and 23.68 ± 2.4 mg%, while there were no hemoglobin and red blood cells in urine. After mini-marathon running, total protein, albumin, hemoglobin and red blood cells in urine were 306.86 ± 60.5 mg/24 hr, 76.64 ± 14.8 mg/24 hr, 7.4 ± 4.0 mg/24 hr and 212 ± 81 cells/hpf, respectively. Therefore, total protein and albumin in urine were significantly increased (P<0.01) after mini-marathon running. Hemoglobinuria and hematuria occurred 16% and 26% of all subjects respectively. We found a significant correlation between hematuria and albuninuria (r = 0.75, P<0.01) after mini-marathon running. Although, no significant difference in urine hemoglobin in subjects between pre and post mini-marathon running, plasma hemoglobin of the subjects ware shoes with thin soles was markedly increased. It is concluded that determination of hematuria, microvascular hemolysis and proteinuria after minimarathon running may occur in those runners with shoes of thin soles.xii, 97 leaves : ill.application/pdfengผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้าHematuriaHemolysisRunningMaster ThesisMahidol University