Bunyarat RungtaweevoranitAkkarapol ButsuriKrittaphat WongmaKaroon SadornKitjanit NeranonChakkrapan NerungsiTienthong ThongpanchangMahidol UniversityThailand National Center for Genetic Engineering and Biotechnology2018-06-112018-06-112012-04-04Tetrahedron Letters. Vol.53, No.14 (2012), 1816-181818733581004040392-s2.0-84857789975https://repository.li.mahidol.ac.th/handle/20.500.14594/13762Thiophene end-capped aromatic analogues, that is, naphthothiophenes, naphthodithiophenes, pyrenothiophene, and benzotrithiophene, can be prepared from commercially available hydroxyarenes in two steps, including (1) a consecutive acid-mediated nucleophilic aromatic substitution of hydroxyarenes with 2-mercaptoethanol, followed by cyclization to form an arene-fused dihydrothiophene, and (2) oxidation of the dihydrothiophene unit to thiophene. © 2012 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/j.tetlet.2012.01.122