Yaqin FanCong WangLiping WangArthit ChairoungduaPawinee PiyachaturawatPeng FuWeiming ZhuGuangxi University for NationalitiesOcean University of ChinaMahidol UniversityGuizhou Medical UniversityQingdao National Laboratory for Marine Science and Technology2019-08-282019-08-282018-08-15Marine Drugs. Vol.16, No.8 (2018)166033972-s2.0-85053718332https://repository.li.mahidol.ac.th/handle/20.500.14594/47302© 2018 by the authors. All Rights Reserved. Two new ansamycins, trienomycins H (1) and I (2), together with the known trienomycinol (3), were isolated from the fermentation broth of the deep-sea-derived bacterium Ochrobactrum sp. OUCMDZ-2164. Their structures, including their absolute configurations, were elucidated based on spectroscopic analyses, ECD spectra, and Marfey’s method. Compound 1 exhibited cytotoxic effects on A549 and K562 cell lines with IC 50 values of 15 and 23 µM, respectively.Mahidol UniversityPharmacology, Toxicology and PharmaceuticsNew ansamycins from the deep-sea-derived bacterium ochrobactrum sp. OUCMDZ-2164ArticleSCOPUS10.3390/md16080282