Juthatip KumpanichTrinuch EiampongpaiboonWidchaya KanchanavasitaSomsak ChitmongkolsukJindaporn PuripattanavongMahidol UniversityPrince of Songkla University2020-12-282020-12-282020-01-01Dental Materials Journal. Vol.39, No.6 (2020), 1016-102118811361028745472-s2.0-85097210221https://repository.li.mahidol.ac.th/handle/123456789/60456© 2020, Japanese Society for Dental Materials and Devices. All rights reserved. The purpose of this study was to evaluate anti-candidal activity, gelation time, and surface hardness of a short-term soft lining material incorporated with varying concentrations of Piper betle extract (0.25 to 20% w/w). Agar-diffusion assay was conducted to evaluate an inhibitory effect against Candida albicans. The gelation time was assessed and surface hardness was measured at 2 h and 7 days by Shore AO durometer. A soft liner containing at least 5% w/w of P. betle extract was observed the inhibitory effect against C. albicans. An increasing of P. betle concentrations provided larger inhibition zone. Incorporating 5% w/w of P. betle extract into the soft liner did not significantly alter its gelation time and surface hardness (ANOVA; p>0.05). The optimum composition at 5% w/w of P. betle extract can be used as an additive in the soft liner to provide the anti-candidal activity without significantly affect these two main properties.Mahidol UniversityDentistryMaterials ScienceArticleSCOPUS10.4012/dmj.2019-314