V. SuvatteS. TuchindaMahidol University2018-03-222018-03-221973-12-01Journal of the Medical Association of Thailand. Vol.56, No.11 (1973), 634-644012522082-s2.0-0015757770https://repository.li.mahidol.ac.th/handle/20.500.14594/10166The results of the combination of L asparaginase and prednisolone for the induction of remission in acute leukemia of childhood were reported. A complete remission was achieved in 12 (75%) out of 16 cases of acute lymphoblastic leukemia within two weeks and in 2 (40%) out of 5 cases of acute myeloblastic leukemia. Serious side effects were few, many biochemical disturbances were observed, but these were well tolerated and reversible. The combination of prednisolone to L asparaginase may reduce the incidence of hypersensitivity reactions.Mahidol UniversityMedicineArticleSCOPUS