Preecha PhuwapraisirisanKnokwan SawangPongpun SiripongSanti Tip-pyangMahidol UniversityChulalongkorn UniversityNational Cancer Institute Thailand2018-08-242018-08-242007-07-23Tetrahedron Letters. Vol.48, No.30 (2007), 5193-5195004040392-s2.0-34250855030https://repository.li.mahidol.ac.th/handle/20.500.14594/24161In the search for antitumor compounds from Bipolaris oryzae, the coexistence of ophiobolins and cochlioquinones is reported for the first time. Of the compounds isolated, anhydrocochlioquinone A (7) was identified as a new antitumor agent. The structure of 7 was fully characterized by spectroscopic data, including COSY, HSQC, HMBC, and NOESY. The cytotoxicity of isolated compounds against HeLa and KB cells is also described. © 2007 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/j.tetlet.2007.05.151