Sumalee KamchonwongpaisanSumpan PaitayatatYodhathai ThebtaranonthPrapin WilairatYongyuth YuthavongMahidol University2018-07-042018-07-041995-06-01Journal of Medicinal Chemistry. Vol.38, No.13 (1995), 2311-231615204804002226232-s2.0-0029044399https://repository.li.mahidol.ac.th/handle/123456789/17239Various derivatives of artemisinin covalently linked to iron chelators were synthesized, and their antimalarial activities were evaluated. Although results show no indication that the presence of an iron chelator in the vicinity of artemisinin potentiates its action, the linked compounds prepared still retain comparable activities to that of artemisinin. © 1995, American Chemical Society. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyPharmacology, Toxicology and PharmaceuticsMechanism-Based Development of New Antimalarials: Synthesis of Derivatives of Artemisinin Attached to Iron ChelatorsArticleSCOPUS10.1021/jm00013a007