Pawana PusuwanSuttipong WacharasindhuViyada AttanathoSunanta ChiewvitSupawadee LikitmaskulSomlak IntarasuphtJiraporn MungkharakRudee PleehachindaMahidol University2018-07-042018-07-041998-08-01Journal of the Medical Association of Thailand. Vol.81, No.8 (1998), 596-601012522082-s2.0-2442442368https://repository.li.mahidol.ac.th/handle/20.500.14594/18503The presence or absence of thyroid glandular tissue demonstrated by thyroid scintigraphy is important for genetic and prognostic counseling and for acceleration of diagnosis in other affected siblings. Technetium-99m-pertechnetate thyroid scintigraphy was performed on 27 children with cretinism at the Division of Nuclear Medicine, Faculty of Medicine Siriraj Hospital during the 5-year period from June 1991. Based on scintigraphic findings, three main groups of thyroid localization were seen. Thirteen (48.1%) were athyrotic while 3 (11.1%) had an ectopic thyroid and 11 (40.8%) had gland in normal position. Perchlorate discharge test was performed in 8 children of the last group and the results were positive indicating an organification defect. Thyroid scintigraphy and perchlorate discharge test provided the useful information for diagnosis, follow-up, and prognosis in children with cretinism.Mahidol UniversityMedicineArticleSCOPUS