Pakorn BovonsombatRameez AliChiraphorn KhanJuthamard LeykajarakulKawin Pla-OnSuraj AphimanchindakulNatchapon PungcharoenpongNisit TimsueaAnchalee ArunratNapat PunpongjareornMahidol University2018-09-242018-09-242010-08-21Tetrahedron. Vol.66, No.34 (2010), 6928-6935004040202-s2.0-77955466444https://repository.li.mahidol.ac.th/handle/20.500.14594/28654para-Regioselective bromination of phenol and analogues, promoted by p-toluenesulfonic acid, is achieved in high to excellent yields at room temperature with N-bromosuccinimide. Chlorination with N-chlorosuccinimide and catalysed by p-toluenesulfonic acid also gives para-chlorinated phenol analogues in good yields at room temperature. para-Bromination of phenol, promoted by p-toluenesulfonic acid, is achieved in excellent yields at room temperature with N-bromosuccinimide. p-Toluenesulfonic acid is also effective as a promoter of para-chlorination with N-chlorosuccinimide. © 2010 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsFacile p-toluenesulfonic acid-promoted para-selective monobromination and chlorination of phenol and analoguesArticleSCOPUS10.1016/j.tet.2010.06.041