Jittra KornsakulkarnKulvadee DolsophonNattawut BoonyuenTanapong BoonruangprapaPranee RachtaweeSamran PrabpaiPalangpon KongsaereeChawanee ThongpanchangThailand National Center for Genetic Engineering and BiotechnologyMahidol University2018-05-032018-05-032011-09-30Tetrahedron. Vol.67, No.39 (2011), 7540-754714645416004040202-s2.0-80052021231https://repository.li.mahidol.ac.th/handle/20.500.14594/11467Eleven new dihydronaphthalenones 1-11, together with five known compounds; 5-hydroxydihydrofusarubin C (12), javanicin, bostr ycoidin, anhydrofusarubin, and 3-O-methylfusarubin, were isolated from the endophytic fungus Fusarium sp. BCC14842. Structures were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. Javanicin, 3-O-methylfusarubin, compounds 3 and 7 exhibited antimycobacterial and cytotoxic activities. Javanicin also displayed antifungal activity with IC 50 of 6.16 μg/mL, while compounds 2, 4, 5, 8, and 12 showed only cytotoxic activity. © 2011 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsArticleSCOPUS10.1016/j.tet.2011.07.078