Phatchanat KlaihmonSudjit LuanpitpongChanchao LorthongpanichChuti LaowtammathronSupaporn WaeteekulPapussorn TerbtoSurapol IssaragrisilSiriraj Hospital2022-08-042022-08-042021-08-01Stem Cell Research. Vol.55, (2021)18767753187350612-s2.0-85111051321https://repository.li.mahidol.ac.th/handle/20.500.14594/76092Natural killer (NK) cells were isolated from human umbilical cord blood from a healthy newborn and reprogrammed by episomal vectors carrying reprograming factors L-MYC, LIN28, OCT4, SOX2, KLF4, EBNA-1, and shRNA against p53 delivered using nucleofection. The obtained MUSIi013-A human induced pluripotent stem cell (iPSC) line highly expressed pluripotency markers, had the capacity to differentiate into derivatives of the three germ layers, while retained a normal karyotype. This cell line may be a useful tool to study epigenic memory that may predispose hiPSCs to enhanced NK differentiation.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyArticleSCOPUS10.1016/j.scr.2021.102472