Mayfong MayxayRattanaxay PhetsouvanhSamlane PhompidaPaul N. NewtonManiphone KhanthavongBouakham VannachoneAlan BrockmanNicholas J. WhiteNational University of LaosMahosot HospitalParasitology and EntomologyJohn Radcliffe HospitalMahidol UniversityShoklo Malaria Research Unit2018-07-242018-07-242003-05-01Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.97, No.3 (2003), 343-344003592032-s2.0-4444234983https://repository.li.mahidol.ac.th/handle/20.500.14594/20907Between June and October 2000 we conducted the first randomized trial in Laos comparing chloroquine (CQ) with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated Plasmodium falciparum malaria (n = 29, 42-d follow-up, age > 5 years). The proportion of patients with treatment failure was high (CQ = 78%, RIII 46%; SP = 36%, RIII 15%). The treatment policy for uncomplicated P. falciparum malaria in Laos needs to be reviewed urgently. © 2003 Royal Society of Tropical Medicine and Hygiene.Mahidol UniversityImmunology and MicrobiologyArticleSCOPUS10.1016/S0035-9203(03)90165-9