Stereoselective synthesis of β-carboethoxy-γ-lactams via imino Mukaiyama aldol-type reaction of 1,4-bis(trimethylsilyloxy)-1,4-diethoxy-1,3-butadiene

Manat PohmakotrNattawut YotapanPatoomratana TuchindaChutima KuhakarnVichai ReutrakulMahidol University2018-08-242018-08-242007-05-14Tetrahedron. Vol.63, No.20 (2007), 4328-4337004040202-s2.0-34047262894https://repository.li.mahidol.ac.th/handle/20.500.14594/24197The reaction of the (bis)trimethylsilyloxy derivative of diethyl succinate with imines in the presence of ZnCl2provides a general stereoselective entry to β-carboethoxy-γ-lactams. © 2007 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsStereoselective synthesis of β-carboethoxy-γ-lactams via imino Mukaiyama aldol-type reaction of 1,4-bis(trimethylsilyloxy)-1,4-diethoxy-1,3-butadieneArticleSCOPUS10.1016/j.tet.2007.03.006