Kulthanachairojana N.Mahidol University2023-06-182023-06-182022-01-01Journal of Dermatological Treatment Vol.33 No.8 (2022) , 3165-316909546634https://repository.li.mahidol.ac.th/handle/20.500.14594/86299Background: Cryotherapy is typically performed by physicians. No cost-utility studies of home-based cryotherapy have been reported. Objectives: To study the cost utility of home-based cryotherapy devices and in-hospital liquid nitrogen therapy for cutaneous warts. Materials and methods: This randomized, controlled, investigator-blinded trial was carried out on patients with cutaneous warts. Participants were randomly assigned to two groups: home-based cryotherapy and in-hospital liquid nitrogen therapy. Clinical examinations were conducted at baseline and monthly until cure, and outcomes (cure rate, side effects, total costs, and quality of life) were compared. A cost-utility analysis was performed. Results: Nineteen of 22 patients completed the treatment and were analyzed. The efficacy of home-based cryotherapy and in-hospital therapy was 72.8% and 64.3%, respectively. Side effects (pain, redness, and burning) were observed. The mean numbers of medical visits were 2.83 for home-based therapy and 3.30 for in-hospital therapy. The total costs for home-based therapy and the in-hospital therapy were US $76.03 and $100.45, respectively. The home-based therapy had 0.2297 quality-adjusted life years, slightly higher than the corresponding value of 0.2254 for in-hospital therapy. Conclusions: Home-based cryotherapy devices are a cost-saving strategy with similar efficacy to in-hospital liquid nitrogen therapy.MedicineArticleSCOPUS10.1080/09546634.2022.21147822-s2.0-851366703941471175335993772