Synthesis of deepoxy-4,5-didehydromethylenomycin a and methylenomycin a methyl esters

C. MahidolC. ThebtaranonthY. ThebtaranonthC. YenjaiMahidol University2018-06-142018-06-141989-01-01Tetrahedron Letters. Vol.30, No.29 (1989), 3857-3860004040392-s2.0-0024359306https://repository.li.mahidol.ac.th/handle/20.500.14594/15719[±]-Deepoxy-4,5-didehydromethylenomycin A methyl ester 8 and [±] -methylenomycin A methyl ester 9 are synthesized from anthracene adduct 2 via a common intermediate 13. Flash vacuum pyrolysis of adduct 13 gives 8, while stereospecific epoxidation of 13 followed by pyrolysis yields 9. © 1989.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistryPharmacology, Toxicology and PharmaceuticsSynthesis of deepoxy-4,5-didehydromethylenomycin a and methylenomycin a methyl estersArticleSCOPUS10.1016/S0040-4039(01)80677-8