Boongird A.Songkwamcharoen T.Mongkolpech W.Kittitirapong N.Mahidol University2024-08-112024-08-112024-02-05International Journal of Surgery Open Vol.62 No.2 (2024) , 109-11524058572https://repository.li.mahidol.ac.th/handle/20.500.14594/100426Introduction: Venous thromboembolism (VTE) is a common complication in neurosurgical procedures both before and after surgery. Objective: To examine the incidence of VTE in neurosurgical patients before surgery and in the postoperative period after implementing a VTE prophylaxis protocol. The authors also aimed to determine VTE risk factors. Methods: The authors conducted a retrospective cohort study examining 200 patients admitted to the hospital for cranial and spine neurosurgical procedures between January 2020 and October 2021. All patients were screened for VTE using a protocol combining measurement of D-dimer level and venous duplex ultrasonography. Patients who screened negative for VTE were evaluated for VTE risk using the Caprini risk assessment model; those with Caprini score greater than or equal to 3 (indicating moderate-to-high risk) received VTE prophylaxis using intermittent pneumatic compression devices. Results: Preoperative screening demonstrated deep venous thrombosis (DVT) in seven of 200 patients (3.5%). All DVTs were asymptomatic and proximal in location. Univariate logistic regression showed that stroke, neurodegenerative disease, and confinement to bed for more than 72 h were significant predictors of preoperative DVT. Among the patients without DVT on preoperative screening, 179 (93%) had a Caprini score greater than or equal to 3; intermittent pneumatic compression was used for prophylaxis in 173 of these (96.6%). Incidence of postoperative VTE was 2.6% (5/193). Extended length of hospital stay, postoperative hydrocephalus, and infection were significant risk factors for VTE. Conclusion: Preoperative VTE screening using D-dimer level and V-DUS and implementation of VTE prophylaxis using IPC can reduce the incidence of VTE and VTE-related mortality in neurosurgical patients.MedicineIncidence and risk factors of venous thromboembolism in neurosurgical patients after implementing a screening protocol: a retrospective cohort study of a tertiary centerArticleSCOPUS10.1097/IO9.00000000000000262-s2.0-85200380650