Chamlong DisayavanishPichet UdomratnDuangjai KasantikulThienchai NgamtipwatthanaPoonsri RangseekajeePramote SukanichTaweesin VisanuyothinManit SrisurapanontPrimprao DisayavanishPongsatorn NetrakomSrichan PhornchirasilpPaitoon SamuthrsindhKittiwan Thiam-KaewChiang Mai UniversityPrince of Songkla UniversityChulalongkorn UniversityPhramongkutklao College of MedicineMahidol UniversityKhon Kaen UniversitySrithanya HospitalSuanprung Psychiatric HospitalSomdet Chaopraya Hosp.2018-09-072018-09-072000-01-01Journal of the Medical Association of Thailand. Vol.83, No.6 (2000)012522082-s2.0-0347113400https://repository.li.mahidol.ac.th/handle/123456789/26353The authors proposed to develop an evidence-based guideline relevant to drug use for treatment-resistant schizophrenia (TRS), which will be called "Guideline for the Pharmacotherapy of Treatment-Resistant Schizophrenia or PTRS Guideline". The authors performed a MEDLINE search (between 1966 and December 1998) and classified the study designs of those trials by using the system proposed by the Agency for Health Care Policy and Research (AHCPR). The levels of evidence were graded and recommendations were made by the use of a system modified from that of the AHCPR. One hundred and sixty-three articles met the inclusion criteria for the review. For a schizophrenic patient who does not respond to a classical antipsychotic.Mahidol UniversityMedicineArticleSCOPUS