C. J. SmithM. JonesD. A.B. DanceW. ChaowagulN. J. WhiteFaculty of Science and InnovationMahidol UniversityJohn Radcliffe HospitalSappasitthiprasong HospitalLondon School of Hygiene & Tropical Medicine2018-08-102018-08-101991-01-01World Journal of Microbiology and Biotechnology. Vol.7, No.1 (1991), 29-3615730972095939932-s2.0-0042673244https://repository.li.mahidol.ac.th/handle/123456789/22013An ELISA system for the detection of human antibodies to Pseudomonas pseudomallei exotoxin is described. Analysis of control sera and sera from patients with culture-positive melioidosis showed that both IgG and IgM antibodies to exotoxin were detectable in patients with melioidosis. This implies that the exotoxin is produced in vivo by P. pseudomallei, and may be involved in the pathogenesis of melioidosis. Furthermore, these rapid and simple assays may prove to be useful for the serodiagnosis of the disease. © 1991, Rapid Communications of Oxford Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyArticleSCOPUS10.1007/BF02310916