Somporn SrifeungfungChanwit TribuddharatSopita ComerungseeTanittha ChatsuwanVipa TreerauthanaweeraphongPimpha RungnobhakhunPongpun NunthapisudKulkanya ChokephaibulkitMahidol UniversityChulalongkorn UniversityQueen Sirikit National Institute of Child HealthBhumipol Aduljadej Hospital2018-09-242018-09-242010-04-26Vaccine. Vol.28, No.19 (2010), 3440-34440264410X2-s2.0-77950515964https://repository.li.mahidol.ac.th/handle/123456789/28731The serotype of 172 S. pneumoniae isolates obtained from normally sterile sites from January 2006 to February 2009 in Thai patients was evaluated. The most common serotypes were 6B, 23F, 14, 19F, and 19A in patients <5 year-old, and 6B, 19A, 23F, 4, 9V in patients >65-year old. Seven-valent pneumococcal conjugated vaccine (PCV-7) covered 70.3%, 43.6%, and 43.5% of patients <5, 5-64 and ≥65 years of age, respectively, while PCV-13 covered 81.2%, 59.7%, and 60.9%, respectively. PCV-9, PCV-10, PCV-11 had very similar coverage as PCV-7. The antibiotic susceptibility rates of the isolates from sterile sites were 88.7-95.7% for penicillin, 90.6-98.4% for cefotaxime, 92.2-100% for ofloxacin and 100% for ciprofloxacin. PCV-7 covered 83% and 100%, respectively, of penicillin and cefotaxime non-susceptible isolates in patients <5-year old. © 2010 Elsevier Ltd. All rights reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicineArticleSCOPUS10.1016/j.vaccine.2010.02.071