Saranya AuparakkitanonPrapon WilairatFaculty of Medicine Ramathibodi Hospital, Mahidol UniversityMahidol University2022-08-042022-08-042021-01-01Biomolecular Concepts. Vol.12, No.1 (2021), 129-1311868503X186850212-s2.0-85115296662https://repository.li.mahidol.ac.th/handle/123456789/76334A unique feature of eukaryote initiation of protein translation is a so-called scanning of 5′-untranslated region (5′-UTR) by a ribosome initiation complex to enable bound Met-tRNAi access to the initiation codon located further downstream. Here, we propose a universal scanning-free translation initiation model that is independent of 5′-UTR length and applicable to both 5′-m7G (capped) and uncapped mRNAs.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyNeuroscienceArticleSCOPUS10.1515/bmc-2021-0014