Somrutai PoothongSuwanna Kitpati BoontanonNarin BoontanonMahidol UniversityFaculty of Environment and Resource Studies, Mahidol University2018-06-112018-06-112012-02-29Journal of Hazardous Materials. Vol.205-206, (2012), 139-14318733336030438942-s2.0-84856214370https://repository.li.mahidol.ac.th/handle/20.500.14594/14203This research aimed to monitor the amounts of PFOS and PFOA in food packaging and study the migration of PFOS and PFOA from food packaging, using a saliva simulant and pressurized liquid extraction (PLE) technique. Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was employed to determine residues of PFOS and PFOA by using a gradient reversed-phase method with ammonium acetate/acetonitrile buffer. A good linearity was established for PFOS and PFOA in a range of 0.05-10μgL -1 , with R 2 ≥0.9998. Of the samples extracted by methanol, the highest concentration of PFOS was found in fast-food container samples, at a level of 92.48ngdm -2 . For PFOA, the highest concentration in samples extracted by methanol was found in ice cream cup samples, at a level of 16.91ngdm -2 . The amounts of PFOS and PFOA that migrated from food packaging samples through contact with saliva simulant were 4.80 and 4.55ngdm -2 , respectively. Saliva simulant could leach PFOS and PFOA from the group of the thickest paper samples (≤1dm 2 g -1 ) at levels of 7.01 and 6.41ngdm -2 , respectively, indicating that paper with greater thickness and less area might release larger quantities of coated/added PFOS or PFOA. © 2011 Elsevier B.V.Mahidol UniversityEnvironmental ScienceArticleSCOPUS10.1016/j.jhazmat.2011.12.050