Anon SrikiatkhachornAlan L. RothmanRobert V. GibbonsNopporn SittisombutPrida MalasitFrancis A. EnnisSuchitra NimmannityaSiripen KalayanaroojUniversity of Massachusetts Medical SchoolUniversity of Rhode IslandArmed Forces Research Institute of Medical Sciences, ThailandFaculty of Medicine, Chiang Mai UniversityMahidol UniversityQueen Sirikit National Institute of Child Health2018-05-032018-05-032011-09-15Clinical Infectious Diseases. Vol.53, No.6 (2011), 563-56715376591105848382-s2.0-80052191667https://repository.li.mahidol.ac.th/handle/20.500.14594/12317Dengue has emerged as a major public health problem worldwide. Dengue virus infection causes a wide range of clinical manifestations. Since the 1970s, clinical dengue has been classified according to the World Health Organization guideline as dengue fever and dengue hemorrhagic fever. The classification has been criticized with regard to its usefulness and its applicability. In 2009, the World Health Organization issued a new guideline that classifies clinical dengue as dengue and severe dengue. The 2009 classification differs s ignificantly from the previous classification in both conceptual and practical levels. The impacts of the new classification on clinical practice, dengue research, and public health policy are discussed. © 2011 The Author.Mahidol UniversityMedicineReviewSCOPUS10.1093/cid/cir451