Actin-based motility of Burkholderia thailandensis requires a central acidic domain of BimA that recruits and activates the cellular Arp2/3 complex

Chayada SitthidetJoanne M. StevensTerence R. FieldAbigail N. LaytonSunee KorbsrisateMark P. StevensMahidol UniversityThe Pirbright Institute2018-09-242018-09-242010-10-01Journal of Bacteriology. Vol.192, No.19 (2010), 5249-525210985530002191932-s2.0-77957356724https://repository.li.mahidol.ac.th/handle/20.500.14594/28633Burkholderia species use BimA for intracellular actin-based motility. Uniquely, Burkholderia thailandensis BimA harbors a central and acidic (CA) domain. The CA domain was required for actin-based motility, binding to the cellular Arp2/3 complex, and Arp2/3-dependent polymerization of actin monomers. Our data reveal distinct strategies for actin-based motility among Burkholderia species. Copyright © 2010, American Society for Microbiology. All Rights Reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyActin-based motility of Burkholderia thailandensis requires a central acidic domain of BimA that recruits and activates the cellular Arp2/3 complexArticleSCOPUS10.1128/JB.00608-10