Linn A.K.Phanthong P.Pewkliang Y.Laosee W.Tong-Ngam P.Tubsuwan A.Trachoo O.Asavapanumas N.Borwornpinyo S.Hongeng S.Yingchoncharoen T.Mahidol University2025-12-122025-12-122025-12-01Stem Cell Research Vol.89 (2025)18735061https://repository.li.mahidol.ac.th/handle/123456789/113477The MUi040-A human induced pluripotent stem cell (hiPSC) line was established from CD34 + hematopoietic stem cells of a male patient with senile amyloidosis. Patient carries a unique chromosome inversion at bands 9p12 and 9q13, which is one of the most common variants of the normal karyotype of chromosome 9 (inv[9]). This hiPSC line maintains an identical karyotype to that of the parental cells. MUi040-A expressed pluripotency markers and demonstrated the capacity to differentiate into all three germ layers. This cell line offers a valuable in vitro for studying the pathophysiology of senile systemic amyloidosis and for evaluating potential therapeutic approaches.Biochemistry, Genetics and Molecular BiologyMedicineArticleSCOPUS10.1016/j.scr.2025.1038662-s2.0-1050238704491876775341223746