B. SuyamudD. InthornB. PanyapinyopolP. ThiravetyanSouth Carolina Commission on Higher EducationMahidol UniversityKing Mongkut s University of Technology Thonburi2019-08-232019-08-232018-11-01Water, Air, and Soil Pollution. Vol.229, No.11 (2018)15732932004969792-s2.0-85055739616https://repository.li.mahidol.ac.th/handle/123456789/45866© 2018, Springer Nature Switzerland AG. A novel bacterium, Bacillus megaterium strain ISO-2, capable of the degradation of bisphenol A (BPA), was isolated from wastewater collected from a polycarbonate industry. The bacterium, which was grown on mineral salts medium supplemented with yeast extract, exhibited complete BPA removal from 5 mg L−1 BPA within 72 h. BPA-degrading ability and bacterial growth, however, were inhibited at higher BPA concentrations. Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) analysis revealed several intermediates during the BPA degradation process by B. megaterium strain ISO-2. These intermediates were identified as 4-(2-hydroxypropan-2-yl)phenol, 4-isopropylphenol, 4-isopropenylphenol, benzoic acid, butanoic acid, propanoic acid, benzeneacetic acid, phenylethyl alcohol, 4-hydroxy-3-methoxybenzaldehyde, and phenolic compounds. The possible degradation pathway of BPA was proposed. In addition, strain ISO-2 effectively removed BPA present in the wastewater and could also tolerate high total dissolved solids (TDS) and an alkaline environment. The results indicate that B. megaterium strain ISO-2 is a very effective bacterium for BPA removal from industrial or contaminated wastewaters.Mahidol UniversityEnvironmental ScienceArticleSCOPUS10.1007/s11270-018-3983-y