Y. ChomcharnK. SurathinD. BunnagS. SucharitT. HarinasutaMahidol University2018-04-302018-04-301980-12-01Southeast Asian Journal of Tropical Medicine and Public Health. Vol.11, No.3 (1980), 408-412003836192-s2.0-0019158623https://repository.li.mahidol.ac.th/handle/20.500.14594/11118A single dose of 45 mg of primaquine base was effective in the elimination of gametocytes of the possibly chloroquine-resistant P. falciparum in Thailand. The gametocyte counts decreased markedly within 3.5 days, showing a significant difference from the control in which gametocytes mostly still remain within 11.4 days. The development of the gametocytes in A. dirus was not observed after treatment. Primaquine can be used as a gametocytocide and sporontocide for falciparum malaria in Thailand if the drug is administered when matured gametocytes appear in the peripheral blood.Mahidol UniversityMedicineArticleSCOPUS