Stuart D. BlacksellAmpai TanganuchitcharnchaiRichard G. JarmanRobert V. GibbonsDaniel H. ParisMark S. BaileyNicholas P J DayRanjan PremaratnaDavid G. LallooH. Janaka De SilvaMahidol UniversityUniversity of OxfordArmed Forces Research Institute of Medical Sciences, ThailandRoyal Centre for Defence MedicineUniversity of KelaniyaLiverpool School of Tropical Medicine2018-05-032018-05-032011-10-01Clinical and Vaccine Immunology. Vol.18, No.10 (2011), 1773-17751556679X155668112-s2.0-80053447095https://repository.li.mahidol.ac.th/handle/123456789/11465A Sri Lankan fever cohort (n = 292 patients; 17.8% prevalence) was used to assess two standard diagnostic Chikungunya IgM tests. The immunochromatographic test (ICT) acute sample sensitivity (SN) was 1.9 to 3.9%, and specificity (SP) was 92.5 to 95.0%. The enzyme-linked immunosorbent assay (ELISA) gave an acute sample SN of 3.9% and an SP of 92.5% and a convalescent sample SN of 84% and an SP of 91%. These assays are not suitable for the acute diagnosis of Chikungunya virus infection. Copyright © 2011, American Society for Microbiology. All Rights Reserved.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicineArticleSCOPUS10.1128/CVI.05288-11