Synthesis of 3-substituted quinolin-2(1H)-ones via the cyclization of o-alkynylisocyanobenzenes

Ailada CharoenpolJatuporn MeesinOnnicha KhaikateVichai ReutrakulManat PohmakotrPawaret LeowanawatDarunee SoorukramChutima KuhakarnMahidol University2019-08-232019-08-232018-01-01Organic and Biomolecular Chemistry. Vol.16, No.38 (2018), 7050-7054147705202-s2.0-85054405734https://repository.li.mahidol.ac.th/handle/123456789/45273© The Royal Society of Chemistry. A facile synthesis of various functionalized 3-substituted quinolin-2(1H)-ones through Ag(i) nitrate-catalyzed cyclization of o-alkynylisocyanobenzenes is described. The reaction allows rapid and convenient access to 3-substituted quinolin-2(1H)-one scaffolds in moderate to good yields.Mahidol UniversityBiochemistry, Genetics and Molecular BiologyChemistrySynthesis of 3-substituted quinolin-2(1H)-ones via the cyclization of o-alkynylisocyanobenzenesArticleSCOPUS10.1039/c8ob01882k