Direk LimmathurotsakulMatthew T.G. HoldenPaul CouplandErin P. PriceNarisara ChantratitaVanaporn WuthiekanunPremjit AmornchaiJulian ParkhillSharon J. PeacockMahidol UniversityWellcome Trust Sanger InstituteMenzies School of Health ResearchUniversity of CambridgeUniversity of St Andrews, School of Medicine2018-11-092018-11-092014-01-01Journal of Clinical Microbiology. Vol.52, No.9 (2014), 3418-34211098660X009511372-s2.0-84906879090https://repository.li.mahidol.ac.th/handle/20.500.14594/34791We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei after inoculation and systemic spread. Copyright © 2014 Limmathurotsakul et al.Mahidol UniversityMedicineMicroevolution of Burkholderia pseudomallei during an acute infectionShort SurveySCOPUS10.1128/JCM.01219-14